Generic Name: Valproate

Used to Treat: epilepsy

Seizure Type: All seizure types

Forms of the medicine:


General Info:
What is Depakene?
Depakene (DEH-pah-keen) is a brand name for the commonly used epilepsy drug valproic (val-PRO-ik) acid. It is used in the treatment of partial or absence seizures by itself or as add-on therapy in adults and children 10 years and older. It is also effective in other primary generalized seizures. Sometimes it is used to prevent migraine headache or to treat mood disorder. Depakene comes in the form of gelatine capsules or syrup (liquid). Depakene is not for the people with liver diseases or pancreas diseases, if you have these diseases, be sure to discuss with your doctor before starting Depakene.

How do I take Depakene?
Take this medication exactly as it is prescribed for you. Do not take the medication in larger amounts or longer than recommended by your doctor. Do not change your dosage without your doctor's advice. Tell your doctor if the medication does not seem to work in treating your condition.
Depakene may or may not be taken with food depending on your tendency for upset stomach. However, do try to take in the same manner and at the same time every day. Do not open, chew, or crush the capsules; swallow them whole. If you decide to take them with food, do so every day as this will change the medication’s absorption time. Shake the liquid well just before measuring a dose. To be sure you ingest the correct dose, measure the liquid with a marked measuring spoon or medicine cup. Do not use a regular table spoon. Ask your pharmacist to provide you with one if you do not have a dose-measuring device.

What if I miss a dose?
Take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take an extra dose, unless prescribed by your doctor.

What if I experience side effects?
Various side effects may occur in taking this medicine. Most side effects are not serious and may disappear naturally. Call your doctor if you have any questions concerning your possible side effects. However, do not stop taking your medication without advice from your doctor. They will discuss and recommend possible options. At times it is necessary to continue taking your medication despite these side effects.

There are other side effects that may be serious and indicate that your body is not tolerating the drug properly. Call a doctor right away if these side effects become severe or cause considerable problems in your daily functions. If you experience a change in seizures, severe rash, or allergic reaction contact your doctor immediately as these may indicate potentially life threatening problems.

Contact your physician immediately if you experience any of the following side effects:

  • Unusual bruising or bleeding
  • Tiny purple spots on the skin
  • Unexplained fever
  • Blisters or rash
  • Hives
  • Confusion
  • Difficulty breathing or swallowing
  • Swollen glands
  • Depression
  • Suicidal thoughts
  • Yellowing of the skin or eyes

Keep this medication in its original container, tightly closed, and out of reach of children. Store your prescription at room temperature, away from excess heat and moisture (i.e. not the bathroom). Protect the extended-release capsules and liquid from excessive light. Do not freeze the liquid. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Recommendation for women
Depakene has an FDA pregnancy category of “D” meaning that there is a risk to the developing fetus. If you find or suspect that you are pregnant, talk to your doctor right away about the potential benefits and risks before making any decisions about the use of this medicine. Women who are taking this medication and who wish to become pregnant should discuss treatment options with their physicians before the pregnancy begins.

Other helpful information
Depakene is not for the people with liver diseases or pancreas diseases, if you have these diseases, be sure to discuss with your doctor before starting Depakene. Taking other medications during taking Depakene may cause unexpected side effects or may increase the possibility of side effects, discuss with your doctor if you have to take other medications while you are taking Depakene.

Side Effects

Weight gain, Upset stomach, Tremor, Altered bleeding time, Liver toxicity, Hair loss, Twitching, Poor coordination, Headaches, Dizziness, Blurred or double vision, Drowsiness