Generic Name: Primidone

Used to Treat: epilepsy

Seizure Type: All seizure types

Forms of the medicine:

250 mg. - 1000 mg.

General Info:

What is Mysoline?
Mysoline (MY-soh-leen) is the brand name of the generic medication primidone (PRIM-ih-dohn). Mysoline is used to treat partial seizures with or without secondary generalization and generalized tonic clonic (grand mal) seizures. It is available in liquid and tablet form.

How do I take Mysoline?
Take this medication exactly as it is prescribed for you. Do not take the medication in larger amounts or longer than recommended by your doctor. Do not change your dosage without your doctor's advice. Tell your doctor if the medication does not seem to work in treating your condition.

Swallow each tablet whole. Do not crush or chew the tablet. Mysoline can be taken either with food or without food, but it's important to be consistent throughout the treatment. It may or may not be taken with food. However, try to take it at the same time and in the same manner every day. Mysoline is usually taken once a day at the beginning of treatment. The dosage is gradually increased to three or four times a day. Shake the suspension well before each use. To be sure you ingest the correct dose, measure the liquid with a marked measuring spoon or medicine cup. Do not use a regular table spoon. Ask your pharmacist to provide you with one if you do not have a dose-measuring device.

What if I miss a dose?
Take the missed dose as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. Do not take an extra dose, unless prescribed by your doctor.

What if I experience side effects?
Various side effects may occur in taking this medicine. Most side effects are not serious and may disappear naturally. Call your doctor if you have any questions concerning your possible side effects. However, do not stop taking your medication without advice from your doctor. They will discuss and recommend possible options. At times it is necessary to continue taking your medication despite these side effects.

There are other side effects that may be serious and indicate that your body is not tolerating the drug properly. Call a doctor right away if these side effects become severe or cause considerable problems in your daily functions. If you experience a change in seizures, severe rash, or allergic reaction contact your doctor immediately as these may indicate potentially life threatening problems.

Contact your physician immediately if you experience any of the following side effects:

  • Severe allergic reactions (rashes, hives, difficulty breathing / swallowing, etc)
  • Double vision / unusual eye movements
  • Fever, sore throat, or other signs of infection
  • Mood / mental swings
  • Unusual fatigue
  • Jaundice (yellowing of skin and eyes)
  • Unusual bleeding / bruising
  • Dark urine
  • Bloody nose

Keep this medication in its original container, tightly closed, and out of reach of children. Store your prescription at room temperature, away from excess heat and moisture (i.e. not the bathroom). Do not freeze the liquid. Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Recommendation for women
Safety in pregnancy has not been established. Women who are taking this medication and who wish to become pregnant should discuss treatment options with their physicians before the pregnancy begins.

Other helpful information
Not everyone experiences side effects. There may be other side effects not appearing above. For a complete list, consult your doctor, nurse, or pharmacist. Mysoline may cause drowsiness, dizziness, lightheadedness, and vision changes. These effects may be worse if you take it with alcohol or certain medicines. Do not drive or perform other possibly unsafe tasks until you know how you react to it. Mysoline may contain tartrazine dye. This may cause an allergic reaction in some patients. It may take several weeks for Mysoline to work well. Do not stop taking Mysoline without talking with your doctor. Hormonal birth control, such as birth control pills, may not work as well while you are using Mysoline. Tell your doctor or dentist that you take Mysoline before you receive any medical or dental care, emergency care, or surgery. Because Mysoline has the potential to interact with many other commonly prescribed medications, it is important to let your doctor know if a new drug has been recently prescribed to you to make certain to correct for any potential drug interactions.

Side Effects

Dizziness, Insomnia, Appetite loss, Hyperactivity (children), Drowsiness, Depression, Irritability, Clumsiness, Nausea, Decreased appetite